IASO Bio AI — ICL Discovery

Data Intake

Two explicit contracts: development-dataset lineage and Program candidate systems.

Model development data

Recover row lineage before any fit

Exact row identity → 100% source-derived lineage → recomputed hard components → immutable successor. Acceptance never runs or activates a model.

Blocked before training

Immutable evidence source IDCompleted lineage overlay

Blocked files remain immutable evidence. A correction is a new source, never an overwrite.

Identity

All 1,100 IDs and structures must match.

Coverage

Every required lineage cell and locator must exist.

Components

Structure and provenance are unioned and replayed.

Boundary

Partition or fold crossover blocks acceptance.

Program candidate systems

Batch IDImmutable evidence source ID

Candidate batch artifact (.json)

Preflight does not write CandidateSystems. It verifies artifact SHA-256, complete molecule–formulation–payload–biology–assay context, metric uncertainty, and reviewed physical evidence for every metric. Any blocker prevents the whole import.

Preview is available to signed-in reviewers. Final import requires an administrator.

Round 1 execution funnel

Counts are live registry state, not inferred experimental results.

1. Custody batch

BLOCKED

Upload, preflight, then import a complete batch.

2. READY systems

BLOCKED

Resolve formulation, payload, context, metrics, uncertainty and evidence blockers.

3. Frozen proposal

BLOCKED

Create a fixed-budget preregistered panel in Experiments.

4. Blinded pack

BLOCKED

Freeze an approved blinded execution pack in Prospective Pilot.

Immutable import receipts

No imported candidate batches for this program.